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KMID : 0985520230280010015
Korean Journal of Pancreas and Biliary Tract
2023 Volume.28 No. 1 p.15 ~ p.18
The Practical Multidisciplinary Management of the Indeterminate Biliary Stricture and/or Dilatation -Radiological Differential Diagnosis: Challenging but Essential-
Oh Hyun-Seok

Abstract
The most important aspect of the imaging role for indeterminate bile duct stricture is to make a differential diagnosis on whether the stricture is highly likely to be malignant or benign. Compared to benign stricture, malignant stricture is longer, thicker, and has indistinct outer border and irregularity of the lumen in contrastenhanced computed tomography and magnetic resonance (MR). Also, in the contrast-enhanced portal phase, malignant stricture has a stronger enhancement than the liver parenchyma. There are studies to differentiate between malignant and benign stricture in diffusion weighted image, a functional MR image, but there remains controversial. Sometimes, malignant biliary stricture may be caused by bile duct invasion of gallbladder cancer, pancreatic cancer, hepatocellular carcinoma, biliary metastasis, and lymphoma. Among the potential causes of indeterminate biliary stricture, the characteristics of multifocal biliary stricture mainly suggest benign sclerosing cholangitis, and various external compression factors that cause biliary stricture can be differentiated by radiologic imaging. There are causes of biliary dilatation without obstructive lesion, radiologic diagnosis can be made by considering various characteristics.
KEYWORD
Biliary stricture, Indeterminate biliary stricture, Malignant biliary stricture, Contrast-enhanced CT, MR
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